K Polyak

Affiliations

Dana-Farber Cancer Institute, Boston, USA; Harvard Medical School, Boston, USA.

Publications (21)

Immune Escape during Breast Tumor Progression.

Cancer immunology research

Avec: Carlos R Gil Del Alcazar , Maša Alečković , Kornelia Polyak

Cancer research

Avec: Guillermo Peluffo , Ashim Subedee , Nicholas W Harper , Natalie Kingston , Bojana Jovanović , Felipe Flores , Laura E Stevens , Francisco Beca , Anne Trinh , Chandra Sekhar Reddy Chilamakuri , Evangelia K Papachristou , Katherine Murphy , Ying Su , Andriy Marusyk , Clive S D'Santos , Oscar M Rueda , Andrew H Beck , Carlos Caldas , Jason S Carroll , Kornelia Polyak

A Darwinian perspective on tumor immune evasion.

Biochimica et biophysica acta. Reviews on cancer

Avec: Julieann Puleo , Kornelia Polyak

The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer.

JCI insight

Avec: Michalina Janiszewska , Shayna Stein , Otto Metzger Filho , Jennifer Eng , Natalie L Kingston , Nicholas W Harper , Inga H Rye , Maša Alečković , Anne Trinh , Katherine C Murphy , Elisabetta Marangoni , Simona Cristea , Benjamin Oakes , Eric P Winer , Ian E Krop , Hege G Russnes , Paul T Spellman , Elmar Bucher , Zhi Hu , Koei Chin , Joe W Gray , Franziska Michor , Kornelia Polyak

Report of the First International Symposium on NUT Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Christopher A French , Michael L Cheng , Glenn J Hanna , Steven G DuBois , Nicole G Chau , Christine L Hann , Simone Storck , Ravi Salgia , Matteo Trucco , Jennifer Tseng , Anastasios Stathis , Richard Piekarz , Ulrich M Lauer , Christophe Massard , Kelly Bennett , Shodeinde Coker , Ulrike Tontsch-Grunt , Martin L Sos , Sida Liao , Catherine J Wu , Kornelia Polyak , Sarina A Piha-Paul , Geoffrey I Shapiro

The MCF10 Model of Breast Tumor Progression.

Cancer research

Avec: Julieann Puleo , Kornelia Polyak

Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts.

Cancer cell

Avec: Siri H Strand , Belén Rivero-Gutiérrez , Kathleen E Houlahan , Jose A Seoane , Lorraine M King , Tyler Risom , Lunden A Simpson , Sujay Vennam , Aziz Khan , Luis Cisneros , Timothy Hardman , Bryan Harmon , Fergus Couch , Kristalyn Gallagher , Mark Kilgore , Shi Wei , Angela DeMichele , Tari King , Priscilla F McAuliffe , Julie Nangia , Joanna Lee , Jennifer Tseng , Anna Maria Storniolo , Alastair M Thompson , Gaorav P Gupta , Robyn Burns , Deborah J Veis , Katherine DeSchryver , Chunfang Zhu , Magdalena Matusiak , Jason Wang , Shirley X Zhu , Jen Tappenden , Daisy Yi Ding , Dadong Zhang , Jingqin Luo , Shu Jiang , Sushama Varma , Lauren Anderson , Cody Straub , Sucheta Srivastava , Christina Curtis , Rob Tibshirani , Robert Michael Angelo , Allison Hall , Kouros Owzar , Kornelia Polyak , Carlo Maley , Jeffrey R Marks , Graham A Colditz , E Shelley Hwang , Robert B West

Loss of Kmt2c or Kmt2d drives brain metastasis via KDM6A-dependent upregulation of MMP3.

Nature cell biology

Avec: Marco Seehawer , Zheqi Li , Jun Nishida , Pierre Foidart , Andrew H Reiter , Ernesto Rojas-Jimenez , Marie-Anne Goyette , Pengze Yan , Shaunak Raval , Miguel Munoz Gomez , Paloma Cejas , Henry W Long , Malvina Papanastasiou , Kornelia Polyak

Midkine as a driver of age-related changes and increase in mammary tumorigenesis.

Cancer cell

Avec: Pengze Yan , Ernesto Rojas Jimenez , Zheqi Li , Triet Bui , Marco Seehawer , Jun Nishida , Pierre Foidart , Laura E Stevens , Yingtian Xie , Miguel Munoz Gomez , So Yeon Park , Henry W Long , Kornelia Polyak

Tumor Neoantigens: When Too Much of a Good Thing Is Bad.

Cancer cell

Avec: Anne Trinh , Kornelia Polyak

Intratumoral Heterogeneity: More Than Just Mutations.

Trends in cell biology

Avec: Kunihiko Hinohara , Kornelia Polyak

Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer.

Nature communications

Avec: Jennifer Y Ge , Shaokun Shu , Mijung Kwon , Bojana Jovanović , Katherine Murphy , Anushree Gulvady , Anne Fassl , Anne Trinh , Yanan Kuang , Grace A Heavey , Adrienne Luoma , Cloud Paweletz , Aaron R Thorner , Kai W Wucherpfennig , Jun Qi , Myles Brown , Piotr Sicinski , Thomas O McDonald , David Pellman , Franziska Michor , Kornelia Polyak

Premenopausal Plasma Osteoprotegerin and Breast Cancer Risk: A Case-Control Analysis Nested within the Nurses' Health Study II.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Avec: Joanne Kotsopoulos , Emma E McGee , Susana Lozano-Esparza , Judy E Garber , Jennifer Ligibel , Laura C Collins , Kornelia Polyak , Myles Brown , Steven Narod , Rulla M Tamimi , A Heather Eliassen

Early-Life Body Adiposity and the Breast Tumor Transcriptome.

Journal of the National Cancer Institute

Avec: Jun Wang , Cheng Peng , Catherine Guranich , Yujing J Heng , Gabrielle M Baker , Christopher A Rubadue , Kimberly Glass , A Heather Eliassen , Rulla M Tamimi , Kornelia Polyak , Susan Hankinson

Heterogeneity and transcriptional drivers of triple-negative breast cancer.

Cell reports

Avec: Bojana Jovanović , Daniel Temko , Laura E Stevens , Marco Seehawer , Anne Fassl , Katherine Murphy , Jayati Anand , Kodie Garza , Anushree Gulvady , Xintao Qiu , Nicholas W Harper , Veerle W Daniels , Huang Xiao-Yun , Jennifer Y Ge , Maša Alečković , Jason Pyrdol , Kunihiko Hinohara , Shawn B Egri , Malvina Papanastasiou , Raga Vadhi , Alba Font-Tello , Robert Witwicki , Guillermo Peluffo , Anne Trinh , Shaokun Shu , Benedetto Diciaccio , Muhammad B Ekram , Ashim Subedee , Zachary T Herbert , Kai W Wucherpfennig , Anthony G Letai , Jacob D Jaffe , Piotr Sicinski , Myles Brown , Deborah Dillon , Henry W Long , Franziska Michor , Kornelia Polyak

Analytical validation of HER2DX genomic test for early-stage HER2-positive breast cancer.

ESMO open

Avec: M Marín-Aguilera , P Jares , E Sanfeliu , G Villacampa , E Hernández-Lllán , A I Martínez-Puchol , S Shankar , B González-Farré , A G Waks , F Brasó-Maristany , F Pardo , D K Manning , J A Abery , J Curaba , L Moon , O Gordon , P Galván , P Wachirakantapong , O Castillo , C M Nee , P Blasco , T H Senevirathne , V Sirenko , O Martínez-Sáez , A Aguirre , I E Krop , Z Li , P Spellman , O Metzger Filho , K Polyak , P Michaels , J A Puig-Butillé , A Vivancos , J Matito , W Buckingham , C M Perou , P Villagrasa-González , A Prat , J S Parker , L Paré

Cancer-stromal cell interactions in breast cancer brain metastases induce glycocalyx-mediated resistance to HER2-targeting therapies.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Marie-Anne Goyette , Laura E Stevens , Carolyn R DePinho , Marco Seehawer , Jun Nishida , Zheqi Li , Callahan M Wilde , Rong Li , Xintao Qiu , Alanna L Pyke , Stephanie Zhao , Klothilda Lim , Gabrielle S Tender , Jason J Northey , Nicholas M Riley , Henry W Long , Carolyn R Bertozzi , Valerie M Weaver , Kornelia Polyak

JAK-STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States.

Cancer research

Avec: Laura E Stevens , Guillermo Peluffo , Xintao Qiu , Daniel Temko , Anne Fassl , Zheqi Li , Anne Trinh , Marco Seehawer , Bojana Jovanović , Maša Alečković , Callahan M Wilde , Renee C Geck , Shaokun Shu , Natalie L Kingston , Nicholas W Harper , Vanessa Almendro , Alanna L Pyke , Shawn B Egri , Malvina Papanastasiou , Kendell Clement , Ningxuan Zhou , Sarah Walker , Jacqueline Salas , So Yeon Park , David A Frank , Alexander Meissner , Jacob D Jaffe , Piotr Sicinski , Alex Toker , Franziska Michor , Henry W Long , Beth A Overmoyer , Kornelia Polyak

Clinical and translational relevance of intratumor heterogeneity.

Trends in cancer

Avec: Marie-Anne Goyette , Marla Lipsyc-Sharf , Kornelia Polyak

Challenges and opportunities for modeling aging and cancer.

Cancer cell

Avec: Olga Anczuków , Susie Airhart , Jeffrey H Chuang , Lisa M Coussens , George A Kuchel , Ron Korstanje , Sheng Li , Anna Lisa Lucido , Sandra S McAllister , Katerina Politi , Kornelia Polyak , Timothy Ratliff , Gary Ren , Jennifer J Trowbridge , Duygu Ucar , Karolina Palucka

Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ.

Nature communications

Avec: Lina Ding , Ying Su , Anne Fassl , Kunihiko Hinohara , Xintao Qiu , Nicholas W Harper , Sung Jin Huh , Noga Bloushtain-Qimron , Bojana Jovanović , Muhammad Ekram , Xiaoyuan Zi , William C Hines , Maša Alečković , Carlos Gil Del Alcazar , Ryan J Caulfield , Dennis M Bonal , Quang-De Nguyen , Vanessa F Merino , Sibgat Choudhury , Gabrielle Ethington , Laura Panos , Michael Grant , William Herlihy , Alfred Au , Gedge D Rosson , Pedram Argani , Andrea L Richardson , Deborah Dillon , D Craig Allred , Kirsten Babski , Elizabeth Min Hui Kim , Charles H McDonnell , Jon Wagner , Ron Rowberry , Kristie Bobolis , Celina G Kleer , E Shelley Hwang , Joanne L Blum , Simona Cristea , Piotr Sicinski , Rong Fan , Henry W Long , Saraswati Sukumar , So Yeon Park , Judy E Garber , Mina Bissell , Jun Yao , Kornelia Polyak

Réseau de co-auteurs

Kornelia Polyak 20 collaborations

Anne Trinh 6 collaborations

Henry W Long 6 collaborations

Maša Alečković 5 collaborations

Nicholas W Harper 5 collaborations

Bojana Jovanović 5 collaborations

Laura E Stevens 5 collaborations

Marco Seehawer 5 collaborations

Franziska Michor 4 collaborations

Zheqi Li 4 collaborations

Anne Fassl 4 collaborations

Piotr Sicinski 4 collaborations

Xintao Qiu 4 collaborations

Guillermo Peluffo 3 collaborations

Katherine Murphy 3 collaborations

Jun Nishida 3 collaborations

Marie-Anne Goyette 3 collaborations

Malvina Papanastasiou 3 collaborations

So Yeon Park 3 collaborations

Kunihiko Hinohara 3 collaborations

Shaokun Shu 3 collaborations

Myles Brown 3 collaborations

Ashim Subedee 2 collaborations

Ying Su 2 collaborations

Julieann Puleo 2 collaborations

Natalie L Kingston 2 collaborations

Simona Cristea 2 collaborations

Jennifer Tseng 2 collaborations

E Shelley Hwang 2 collaborations

Pierre Foidart 2 collaborations

Pengze Yan 2 collaborations

Miguel Munoz Gomez 2 collaborations

Jennifer Y Ge 2 collaborations

Anushree Gulvady 2 collaborations

Kai W Wucherpfennig 2 collaborations

Judy E Garber 2 collaborations

Rulla M Tamimi 2 collaborations

A Heather Eliassen 2 collaborations

Daniel Temko 2 collaborations

Shawn B Egri 2 collaborations

Jacob D Jaffe 2 collaborations

Deborah Dillon 2 collaborations

Callahan M Wilde 2 collaborations

Alanna L Pyke 2 collaborations

Carlos R Gil Del Alcazar 1 collaboration

Natalie Kingston 1 collaboration

Felipe Flores 1 collaboration

Francisco Beca 1 collaboration

Chandra Sekhar Reddy Chilamakuri 1 collaboration

Evangelia K Papachristou 1 collaboration

Andriy Marusyk 1 collaboration

Clive S D'Santos 1 collaboration

Oscar M Rueda 1 collaboration

Andrew H Beck 1 collaboration

Carlos Caldas 1 collaboration

Jason S Carroll 1 collaboration

Michalina Janiszewska 1 collaboration

Shayna Stein 1 collaboration

Otto Metzger Filho 1 collaboration

Jennifer Eng 1 collaboration

Inga H Rye 1 collaboration

Katherine C Murphy 1 collaboration

Elisabetta Marangoni 1 collaboration

Benjamin Oakes 1 collaboration

Eric P Winer 1 collaboration

Ian E Krop 1 collaboration

Hege G Russnes 1 collaboration

Paul T Spellman 1 collaboration

Elmar Bucher 1 collaboration

Zhi Hu 1 collaboration

Koei Chin 1 collaboration

Joe W Gray 1 collaboration

Christopher A French 1 collaboration

Michael L Cheng 1 collaboration

Glenn J Hanna 1 collaboration

Steven G DuBois 1 collaboration

Nicole G Chau 1 collaboration

Christine L Hann 1 collaboration

Simone Storck 1 collaboration

Ravi Salgia 1 collaboration

Matteo Trucco 1 collaboration

Anastasios Stathis 1 collaboration

Richard Piekarz 1 collaboration

Ulrich M Lauer 1 collaboration

Christophe Massard 1 collaboration

Kelly Bennett 1 collaboration

Shodeinde Coker 1 collaboration

Ulrike Tontsch-Grunt 1 collaboration

Martin L Sos 1 collaboration

Sida Liao 1 collaboration

Catherine J Wu 1 collaboration

Sarina A Piha-Paul 1 collaboration

Geoffrey I Shapiro 1 collaboration

Siri H Strand 1 collaboration

Belén Rivero-Gutiérrez 1 collaboration

Kathleen E Houlahan 1 collaboration

Jose A Seoane 1 collaboration

Lorraine M King 1 collaboration

Tyler Risom 1 collaboration

Lunden A Simpson 1 collaboration

Sujay Vennam 1 collaboration

Aziz Khan 1 collaboration

Luis Cisneros 1 collaboration

Timothy Hardman 1 collaboration

Bryan Harmon 1 collaboration

Fergus Couch 1 collaboration

Kristalyn Gallagher 1 collaboration

Mark Kilgore 1 collaboration

Shi Wei 1 collaboration

Angela DeMichele 1 collaboration

Tari King 1 collaboration

Priscilla F McAuliffe 1 collaboration

Julie Nangia 1 collaboration

Joanna Lee 1 collaboration

Anna Maria Storniolo 1 collaboration

Alastair M Thompson 1 collaboration

Gaorav P Gupta 1 collaboration

Robyn Burns 1 collaboration

Deborah J Veis 1 collaboration

Katherine DeSchryver 1 collaboration

Chunfang Zhu 1 collaboration

Magdalena Matusiak 1 collaboration

Jason Wang 1 collaboration

Shirley X Zhu 1 collaboration

Jen Tappenden 1 collaboration

Daisy Yi Ding 1 collaboration

Dadong Zhang 1 collaboration

Jingqin Luo 1 collaboration

Shu Jiang 1 collaboration

Sushama Varma 1 collaboration

Lauren Anderson 1 collaboration

Cody Straub 1 collaboration

Sucheta Srivastava 1 collaboration

Christina Curtis 1 collaboration

Rob Tibshirani 1 collaboration

Robert Michael Angelo 1 collaboration

Allison Hall 1 collaboration

Kouros Owzar 1 collaboration

Carlo Maley 1 collaboration

Jeffrey R Marks 1 collaboration

Graham A Colditz 1 collaboration

Robert B West 1 collaboration

Andrew H Reiter 1 collaboration

Ernesto Rojas-Jimenez 1 collaboration

Shaunak Raval 1 collaboration

Paloma Cejas 1 collaboration

Ernesto Rojas Jimenez 1 collaboration

Triet Bui 1 collaboration

Yingtian Xie 1 collaboration

Mijung Kwon 1 collaboration

Yanan Kuang 1 collaboration

Grace A Heavey 1 collaboration

Adrienne Luoma 1 collaboration

Cloud Paweletz 1 collaboration

Aaron R Thorner 1 collaboration

Jun Qi 1 collaboration

Thomas O McDonald 1 collaboration

David Pellman 1 collaboration

Joanne Kotsopoulos 1 collaboration

Emma E McGee 1 collaboration

Susana Lozano-Esparza 1 collaboration

Jennifer Ligibel 1 collaboration

Laura C Collins 1 collaboration

Steven Narod 1 collaboration

Jun Wang 1 collaboration

Cheng Peng 1 collaboration

Catherine Guranich 1 collaboration

Yujing J Heng 1 collaboration

Gabrielle M Baker 1 collaboration

Christopher A Rubadue 1 collaboration

Kimberly Glass 1 collaboration

Susan Hankinson 1 collaboration

Jayati Anand 1 collaboration

Kodie Garza 1 collaboration

Veerle W Daniels 1 collaboration

Huang Xiao-Yun 1 collaboration

Jason Pyrdol 1 collaboration

Raga Vadhi 1 collaboration

Alba Font-Tello 1 collaboration

Robert Witwicki 1 collaboration

Benedetto Diciaccio 1 collaboration

Muhammad B Ekram 1 collaboration

Zachary T Herbert 1 collaboration

Anthony G Letai 1 collaboration

M Marín-Aguilera 1 collaboration

P Jares 1 collaboration

E Sanfeliu 1 collaboration

G Villacampa 1 collaboration

E Hernández-Lllán 1 collaboration

A I Martínez-Puchol 1 collaboration

S Shankar 1 collaboration

B González-Farré 1 collaboration

A G Waks 1 collaboration

F Brasó-Maristany 1 collaboration

F Pardo 1 collaboration

D K Manning 1 collaboration

J A Abery 1 collaboration

J Curaba 1 collaboration

L Moon 1 collaboration

O Gordon 1 collaboration

P Galván 1 collaboration

P Wachirakantapong 1 collaboration

O Castillo 1 collaboration

C M Nee 1 collaboration

P Blasco 1 collaboration

T H Senevirathne 1 collaboration

V Sirenko 1 collaboration

O Martínez-Sáez 1 collaboration

A Aguirre 1 collaboration

I E Krop 1 collaboration

Z Li 1 collaboration

P Spellman 1 collaboration

O Metzger Filho 1 collaboration

P Michaels 1 collaboration

J A Puig-Butillé 1 collaboration

A Vivancos 1 collaboration

J Matito 1 collaboration

W Buckingham 1 collaboration

C M Perou 1 collaboration

P Villagrasa-González 1 collaboration

A Prat 1 collaboration

J S Parker 1 collaboration

L Paré 1 collaboration

Carolyn R DePinho 1 collaboration

Rong Li 1 collaboration

Stephanie Zhao 1 collaboration

Klothilda Lim 1 collaboration

Gabrielle S Tender 1 collaboration

Jason J Northey 1 collaboration

Nicholas M Riley 1 collaboration

Carolyn R Bertozzi 1 collaboration

Valerie M Weaver 1 collaboration

Renee C Geck 1 collaboration

Vanessa Almendro 1 collaboration

Kendell Clement 1 collaboration

Ningxuan Zhou 1 collaboration

Sarah Walker 1 collaboration

Jacqueline Salas 1 collaboration

David A Frank 1 collaboration

Alexander Meissner 1 collaboration

Alex Toker 1 collaboration

Beth A Overmoyer 1 collaboration

Marla Lipsyc-Sharf 1 collaboration

Olga Anczuków 1 collaboration

Susie Airhart 1 collaboration

Jeffrey H Chuang 1 collaboration

Lisa M Coussens 1 collaboration

George A Kuchel 1 collaboration

Ron Korstanje 1 collaboration

Sheng Li 1 collaboration

Anna Lisa Lucido 1 collaboration

Sandra S McAllister 1 collaboration

Katerina Politi 1 collaboration

Timothy Ratliff 1 collaboration

Gary Ren 1 collaboration

Jennifer J Trowbridge 1 collaboration

Duygu Ucar 1 collaboration

Karolina Palucka 1 collaboration

Lina Ding 1 collaboration

Sung Jin Huh 1 collaboration

Noga Bloushtain-Qimron 1 collaboration

Muhammad Ekram 1 collaboration

Xiaoyuan Zi 1 collaboration

William C Hines 1 collaboration

Carlos Gil Del Alcazar 1 collaboration

Ryan J Caulfield 1 collaboration

Dennis M Bonal 1 collaboration

Quang-De Nguyen 1 collaboration

Vanessa F Merino 1 collaboration

Sibgat Choudhury 1 collaboration

Gabrielle Ethington 1 collaboration

Laura Panos 1 collaboration

Michael Grant 1 collaboration

William Herlihy 1 collaboration

Alfred Au 1 collaboration

Gedge D Rosson 1 collaboration

Pedram Argani 1 collaboration

Andrea L Richardson 1 collaboration

D Craig Allred 1 collaboration

Kirsten Babski 1 collaboration

Elizabeth Min Hui Kim 1 collaboration

Charles H McDonnell 1 collaboration

Jon Wagner 1 collaboration

Ron Rowberry 1 collaboration

Kristie Bobolis 1 collaboration

Celina G Kleer 1 collaboration

Joanne L Blum 1 collaboration

Rong Fan 1 collaboration

Saraswati Sukumar 1 collaboration

Mina Bissell 1 collaboration

Jun Yao 1 collaboration